Majin Bone Episode 35

●回復したら是非とも聞かねばなりませんね！YOUは何しに地球へ？って。
　Kaifuku shitara zehi tomo kikaneba narimasenne! You ha nani shini chikyuu he tte
― Once they recover, I must ask them everything! Why did you come to Earth?

This line is punned on a popular TV programme name.

Why Did You Come to Japan? (YOUは何しに日本へ？ Yū wa Nani Shi ni Nippon e?) is a Japanese television programme presented by Osamu Shitara and Yūki Himura, a comedy double act together known as "Bananaman". It is a regular programme on TV Tokyo on Monday evenings. (...) In the programme, a team of interviewers go around various locations in Japan, in particular Narita Airport, and ask non-Japanese people "Why did you come to Japan?". They then attempt to follow the interviewees on their journeys around Japan, in a process called mitchaku shuzai (密着取材, lit. "close-contact reporting"). (http://en.wikipedia.org/wiki/Why_Did_You_Come_to_Japan?)

Official website (Japanese)

Majin Bone is broadcasted on TV Tokyo too.